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A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation
BACKGROUND: In mammals, sex determination is genetically controlled. The SRY gene, located on Y chromosome, functions as the dominant genetic switch for testis development. The SRY gene is specifically expressed in a subpopulation of somatic cells (pre-Sertoli cells) of the developing urogenital rid...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387164/ https://www.ncbi.nlm.nih.gov/pubmed/18445271 http://dx.doi.org/10.1186/1471-2199-9-44 |