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A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation

BACKGROUND: In mammals, sex determination is genetically controlled. The SRY gene, located on Y chromosome, functions as the dominant genetic switch for testis development. The SRY gene is specifically expressed in a subpopulation of somatic cells (pre-Sertoli cells) of the developing urogenital rid...

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Detalles Bibliográficos
Autores principales: Miyamoto, Yoko, Taniguchi, Hiroaki, Hamel, Frédéric, Silversides, David W, Viger, Robert S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387164/
https://www.ncbi.nlm.nih.gov/pubmed/18445271
http://dx.doi.org/10.1186/1471-2199-9-44