The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB

Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is an autosomal dominant dementia that is characterized by the retention of polymers of neuroserpin as inclusions within the endoplasmic reticulum (ER) of neurons. We have developed monoclonal antibodies that detect polymerized neuros...

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Detalles Bibliográficos
Autores principales: Miranda, Elena, MacLeod, Ian, Davies, Mark J., Pérez, Juan, Römisch, Karin, Crowther, Damian C., Lomas, David A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387220/
https://www.ncbi.nlm.nih.gov/pubmed/18267959
http://dx.doi.org/10.1093/hmg/ddn041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387220/
https://www.ncbi.nlm.nih.gov/pubmed/18267959
http://dx.doi.org/10.1093/hmg/ddn041

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