Ultrasensitive gene regulation by positive feedback loops in nucleosome modification

Eukaryotic transcription involves the synergistic interaction of many different proteins. However, the question remains how eukaryotic promoters achieve ultrasensitive or threshold responses to changes in the concentration or activity of a single transcription factor (TF). We show theoretically that...

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Detalles Bibliográficos
Autores principales: Sneppen, Kim, Micheelsen, Mille A, Dodd, Ian B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387233/
https://www.ncbi.nlm.nih.gov/pubmed/18414483
http://dx.doi.org/10.1038/msb.2008.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387233/
https://www.ncbi.nlm.nih.gov/pubmed/18414483
http://dx.doi.org/10.1038/msb.2008.21

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