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Ultrasensitive gene regulation by positive feedback loops in nucleosome modification
Eukaryotic transcription involves the synergistic interaction of many different proteins. However, the question remains how eukaryotic promoters achieve ultrasensitive or threshold responses to changes in the concentration or activity of a single transcription factor (TF). We show theoretically that...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387233/ https://www.ncbi.nlm.nih.gov/pubmed/18414483 http://dx.doi.org/10.1038/msb.2008.21 |