In vivo consequences of deleting EGF repeats 8–12 including the ligand binding domain of mouse Notch1

BACKGROUND: Notch signaling is highly conserved in the metazoa and is critical for many cell fate decisions. Notch activation occurs following ligand binding to Notch extracellular domain. In vitro binding assays have identified epidermal growth factor (EGF) repeats 11 and 12 as the ligand binding d...

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Detalles Bibliográficos
Autores principales: Ge, Changhui, Liu, Tongyi, Hou, Xinghua, Stanley, Pamela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390518/
https://www.ncbi.nlm.nih.gov/pubmed/18445292
http://dx.doi.org/10.1186/1471-213X-8-48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390518/
https://www.ncbi.nlm.nih.gov/pubmed/18445292
http://dx.doi.org/10.1186/1471-213X-8-48

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