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Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis

BACKGROUND: A common element among cancer cells is the presence of improperly controlled transcription. In these cells, the degree of specific activation of some genes is abnormal, and altering the aberrant transcription may therefore directly target cancer. TFIIS is a transcription elongation facto...

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Detalles Bibliográficos
Autores principales: Hubbard, Kyle, Catalano, Jennifer, Puri, Raj K, Gnatt, Averell
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390572/
https://www.ncbi.nlm.nih.gov/pubmed/18474089
http://dx.doi.org/10.1186/1471-2407-8-133