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Multiple Host Barriers Restrict Poliovirus Trafficking in Mice
RNA viruses such as poliovirus have high mutation rates, and a diverse viral population is likely required for full virulence. We previously identified limitations on poliovirus spread after peripheral injection of mice expressing the human poliovirus receptor (PVR), and we hypothesized that the hos...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390757/ https://www.ncbi.nlm.nih.gov/pubmed/18535656 http://dx.doi.org/10.1371/journal.ppat.1000082 |