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Multiple Host Barriers Restrict Poliovirus Trafficking in Mice

RNA viruses such as poliovirus have high mutation rates, and a diverse viral population is likely required for full virulence. We previously identified limitations on poliovirus spread after peripheral injection of mice expressing the human poliovirus receptor (PVR), and we hypothesized that the hos...

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Detalles Bibliográficos
Autores principales: Kuss, Sharon K., Etheredge, Chris A., Pfeiffer, Julie K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390757/
https://www.ncbi.nlm.nih.gov/pubmed/18535656
http://dx.doi.org/10.1371/journal.ppat.1000082