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Vascular tube formation on matrix metalloproteinase-1-damaged collagen

Connective tissue damage and angiogenesis are both important features of tumour growth and invasion. Here, we show that endothelial cells maintained on a three-dimensional lattice of intact polymerised collagen formed a monolayer of cells with a cobblestone morphology. When the collagen was exposed...

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Detalles Bibliográficos
Autores principales: Varani, J, Perone, P, Warner, R L, Dame, M K, Kang, S, Fisher, G J, Voorhees, J J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391116/
https://www.ncbi.nlm.nih.gov/pubmed/18443597
http://dx.doi.org/10.1038/sj.bjc.6604357