Adverse prognosis of epigenetic inactivation in RUNX3 gene at 1p36 in human pancreatic cancer

Alteration in transforming growth factor-β signalling pathway is one of the main causes of pancreatic cancer. The human runt-related transcription factor 3 gene (RUNX3) is an important component of this pathway. RUNX3 locus 1p36 is commonly deleted in a variety of human cancers, including pancreatic...

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Detalles Bibliográficos
Autores principales: Nomoto, S, Kinoshita, T, Mori, T, Kato, K, Sugimoto, H, Kanazumi, N, Takeda, S, Nakao, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391125/
https://www.ncbi.nlm.nih.gov/pubmed/18475302
http://dx.doi.org/10.1038/sj.bjc.6604333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391125/
https://www.ncbi.nlm.nih.gov/pubmed/18475302
http://dx.doi.org/10.1038/sj.bjc.6604333

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