The clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis

BACKGROUND: Ligand endocytosis plays a critical role in regulating the activity of the Notch pathway. The Drosophila homolog of auxilin (dAux), a J-domain-containing protein best known for its role in the disassembly of clathrin coats from clathrin-coated vesicles, has recently been implicated in No...

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Detalles Bibliográficos
Autores principales: Kandachar, Vasundhara, Bai, Ting, Chang, Henry C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391152/
https://www.ncbi.nlm.nih.gov/pubmed/18466624
http://dx.doi.org/10.1186/1471-213X-8-50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391152/
https://www.ncbi.nlm.nih.gov/pubmed/18466624
http://dx.doi.org/10.1186/1471-213X-8-50

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