Analysis of the distribution of functionally relevant rare codons

BACKGROUND: The substitution of rare codons with more frequent codons is a commonly applied method in heterologous gene expression to increase protein yields. However, in some cases these substitutions lead to a decrease of protein solubility or activity. To predict these functionally relevant rare...

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Detalles Bibliográficos
Autores principales: Widmann, Michael, Clairo, Marie, Dippon, Jürgen, Pleiss, Jürgen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391168/
https://www.ncbi.nlm.nih.gov/pubmed/18457591
http://dx.doi.org/10.1186/1471-2164-9-207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391168/
https://www.ncbi.nlm.nih.gov/pubmed/18457591
http://dx.doi.org/10.1186/1471-2164-9-207

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