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Expansion of signaling genes for adaptive immune system evolution in early vertebrates

BACKGROUND: The adaptive immune system (AIS) of jawed vertebrates is a sophisticated system mediated by numerous genes in specialized cells. Phylogenetic analysis indicates that emergence of the AIS followed the occurrence of two rounds of whole-genome duplication (2R-WGD) in early vertebrates, but...

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Detalles Bibliográficos
Autores principales: Okada, Kinya, Asai, Kiyoshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391169/
https://www.ncbi.nlm.nih.gov/pubmed/18479507
http://dx.doi.org/10.1186/1471-2164-9-218