Cargando…

Atomic Constraints between the Voltage Sensor and the Pore Domain in a Voltage-gated K(+) Channel of Known Structure

In voltage-gated K(+) channels (Kv), membrane depolarization promotes a structural reorganization of each of the four voltage sensor domains surrounding the conducting pore, inducing its opening. Although the crystal structure of Kv1.2 provided the first atomic resolution view of a eukaryotic Kv cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Lewis, Anthony, Jogini, Vishwanath, Blachowicz, Lydia, Lainé, Muriel, Roux, Benoît
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391244/
https://www.ncbi.nlm.nih.gov/pubmed/18504314
http://dx.doi.org/10.1085/jgp.200809962