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Atomic Constraints between the Voltage Sensor and the Pore Domain in a Voltage-gated K(+) Channel of Known Structure
In voltage-gated K(+) channels (Kv), membrane depolarization promotes a structural reorganization of each of the four voltage sensor domains surrounding the conducting pore, inducing its opening. Although the crystal structure of Kv1.2 provided the first atomic resolution view of a eukaryotic Kv cha...
Autores principales: | Lewis, Anthony, Jogini, Vishwanath, Blachowicz, Lydia, Lainé, Muriel, Roux, Benoît |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391244/ https://www.ncbi.nlm.nih.gov/pubmed/18504314 http://dx.doi.org/10.1085/jgp.200809962 |
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