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Position and Role of the BK Channel α Subunit S0 Helix Inferred from Disulfide Crosslinking

The position and role of the unique N-terminal transmembrane (TM) helix, S0, in large-conductance, voltage- and calcium-activated potassium (BK) channels are undetermined. From the extents of intra-subunit, endogenous disulfide bond formation between cysteines substituted for the residues just outsi...

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Detalles Bibliográficos
Autores principales: Liu, Guoxia, Zakharov, Sergey I., Yang, Lin, Deng, Shi-Xian, Landry, Donald W., Karlin, Arthur, Marx, Steven O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391248/
https://www.ncbi.nlm.nih.gov/pubmed/18474637
http://dx.doi.org/10.1085/jgp.200809968