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A Continuum Method for Determining Membrane Protein Insertion Energies and the Problem of Charged Residues

Continuum electrostatic approaches have been extremely successful at describing the charged nature of soluble proteins and how they interact with binding partners. However, it is unclear whether continuum methods can be used to quantitatively understand the energetics of membrane protein insertion a...

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Detalles Bibliográficos
Autores principales: Choe, Seungho, Hecht, Karen A., Grabe, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391250/
https://www.ncbi.nlm.nih.gov/pubmed/18474636
http://dx.doi.org/10.1085/jgp.200809959