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A Continuum Method for Determining Membrane Protein Insertion Energies and the Problem of Charged Residues
Continuum electrostatic approaches have been extremely successful at describing the charged nature of soluble proteins and how they interact with binding partners. However, it is unclear whether continuum methods can be used to quantitatively understand the energetics of membrane protein insertion a...
Autores principales: | Choe, Seungho, Hecht, Karen A., Grabe, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391250/ https://www.ncbi.nlm.nih.gov/pubmed/18474636 http://dx.doi.org/10.1085/jgp.200809959 |
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