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Pharmacodynamic optimization of β-lactams in the patient care setting
In order to eradicate an infecting organism, it is necessary to achieve or maintain concentrations of an antibiotic in vivo that exceed the minimum inhibitory concentration (MIC) for the organism. Duration of exposure, or time above MIC, was recognized as being important for β-lactam antibiotics mor...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391264/ https://www.ncbi.nlm.nih.gov/pubmed/18495059 http://dx.doi.org/10.1186/cc6818 |