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Bisphosphonates antagonise bone growth factors' effects on human breast cancer cells survival
Bone tissue constitutes a fertile ‘soil’ for metastatic tumours, notably breast cancer. High concentrations of growth factors in bone matrix favour cancer cell proliferation and survival, and a vicious cycle settles between bone matrix, osteoclasts and cancer cells. Classically, bisphosphonates inte...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394205/ https://www.ncbi.nlm.nih.gov/pubmed/12838321 http://dx.doi.org/10.1038/sj.bjc.6601009 |