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Bisphosphonates antagonise bone growth factors' effects on human breast cancer cells survival

Bone tissue constitutes a fertile ‘soil’ for metastatic tumours, notably breast cancer. High concentrations of growth factors in bone matrix favour cancer cell proliferation and survival, and a vicious cycle settles between bone matrix, osteoclasts and cancer cells. Classically, bisphosphonates inte...

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Detalles Bibliográficos
Autores principales:	Fromigue, O, Kheddoumi, N, Body, J-J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394205/ https://www.ncbi.nlm.nih.gov/pubmed/12838321 http://dx.doi.org/10.1038/sj.bjc.6601009

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