Carboxymethyl benzylamide dextran inhibits angiogenesis and growth of VEGF-overexpressing human epidermoid carcinoma xenograft in nude mice

Vascular endothelial growth factor (VEGF) expression is elevated in a wide variety of solid tumours. Inhibition of VEGF activities is able to reduce angiogenesis and tumour growth. We have recently shown in vitro that carboxymethyl dextran benzylamide (CMDB7) prevents the binding of VEGF(165) to its...

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Detalles Bibliográficos
Autores principales: Hamma-Kourbali, Y, Starzec, A, Vassy, R, Martin, A, Kraemer, M, Perret, G, Crépin, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394212/
https://www.ncbi.nlm.nih.gov/pubmed/12838326
http://dx.doi.org/10.1038/sj.bjc.6601029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394212/
https://www.ncbi.nlm.nih.gov/pubmed/12838326
http://dx.doi.org/10.1038/sj.bjc.6601029

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