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AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2
Activation of the serine/threonine kinase AKT is common in pancreatic cancer; inhibition of which sensitises cells to the apoptotic effect of chemotherapy. Of the various downstream targets of AKT, we examined activation of the NF-κB transcription factor and subsequent transcriptional regulation of...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394257/ https://www.ncbi.nlm.nih.gov/pubmed/12865934 http://dx.doi.org/10.1038/sj.bjc.6601037 |