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Microvascular mechanisms by which the combretastatin A-4 derivative AC7700 (AVE8062) induces tumour blood flow stasis
We previously reported that a novel combretastatin A-4 derivative, AC7700, has remarkable antitumour effects because of an irreversible stasis of tumour blood flow (TBF) and subsequent loss of nutrient supply to tumour tissue. Since early 2002, under the new designation AVE8062, AC7700 has undergone...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394288/ https://www.ncbi.nlm.nih.gov/pubmed/14520469 http://dx.doi.org/10.1038/sj.bjc.6601261 |