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The expression of P-glycoprotein does influence the distribution of novel fluorescent compounds in solid tumour models
Solid tumours display a complex drug resistance phenotype that involves inherent and acquired mechanisms. Multicellular resistance is an inherent feature of solid tumours and is known to present significant barriers to drug permeation in tumours. Given this barrier, do acquired resistance mechanisms...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394330/ https://www.ncbi.nlm.nih.gov/pubmed/14562035 http://dx.doi.org/10.1038/sj.bjc.6601300 |