p16 gene transfer increases cell killing with abnormal nucleation after ionising radiation in glioma cells

It is well established that cells synchronised at the G1–S phase are highly radiosensitive. In this study, p16-null human glioma cell lines were induced into G1 cell cycle arrest by adenovirus-mediated p16 gene transfer, and examined for radiation-induced cell killing. Clonogenic analysis and trypan...

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Detalles Bibliográficos
Autores principales: Hama, S, Matsuura, S, Tauchi, H, Yamasaki, F, Kajiwara, Y, Arita, K, Yoshioka, H, Heike, Y, Mandai, K, Kurisu, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394396/
https://www.ncbi.nlm.nih.gov/pubmed/14583787
http://dx.doi.org/10.1038/sj.bjc.6601299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394396/
https://www.ncbi.nlm.nih.gov/pubmed/14583787
http://dx.doi.org/10.1038/sj.bjc.6601299

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