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Functional analysis of the actin-binding protein, tropomyosin 1, in neuroblastoma

Tropomyosin 1 (TM1) is downregulated in a number of transformed cell types, and exogenous expression of TM1 can restore actin organisation and reverse cellular transformation. We find that TM1 is also downregulated in human neuroblastoma cell lines, correlating with increasing malignancy. However, e...

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Detalles Bibliográficos
Autores principales: Yager, M L, Hughes, J A I, Lovicu, F J, Gunning, P W, Weinberger, R P, O'Neill, G M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394486/
https://www.ncbi.nlm.nih.gov/pubmed/12942118
http://dx.doi.org/10.1038/sj.bjc.6601201