Cargando…

Functional analysis of the actin-binding protein, tropomyosin 1, in neuroblastoma

Tropomyosin 1 (TM1) is downregulated in a number of transformed cell types, and exogenous expression of TM1 can restore actin organisation and reverse cellular transformation. We find that TM1 is also downregulated in human neuroblastoma cell lines, correlating with increasing malignancy. However, e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yager, M L, Hughes, J A I, Lovicu, F J, Gunning, P W, Weinberger, R P, O'Neill, G M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394486/ https://www.ncbi.nlm.nih.gov/pubmed/12942118 http://dx.doi.org/10.1038/sj.bjc.6601201

Ejemplares similares

Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells
por: Glass, Joshua J., et al.
Publicado: (2015)

Experience with International Neuroblastoma Staging System and Pathology Classification
por: Ikeda, H, et al.
Publicado: (2002)

Wild-type oestrogen receptor beta (ERβ1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers
por: O'Neill, P A, et al.
Publicado: (2004)

Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27
por: O'Neill, P A, et al.
Publicado: (2004)

Expression of costimulatory molecules in human neuroblastoma. Evidence that CD40+ neuroblastoma cells undergo apoptosis following interaction with CD40L
por: Airoldi, I, et al.
Publicado: (2003)

L523S, an RNA-binding protein as a potential therapeutic target for lung cancer
por: Wang, T, et al.
Publicado: (2003)

Tumour cell contamination of autologous stem cells grafts in high-risk neuroblastoma: the good news?
por: Handgretinger, R, et al.
Publicado: (2003)

Low-dose interferon-γ-producing human neuroblastoma cells show reduced proliferation and delayed tumorigenicity
por: Airoldi, I, et al.
Publicado: (2004)

Correlation of elevated level of blood midkine with poor prognostic factors of human neuroblastomas
por: Ikematsu, S, et al.
Publicado: (2003)

CpG island methylation status and mutation analysis of the RB1 gene essential promoter region and protein-binding pocket domain in nervous system tumours
por: Gonzalez-Gomez, P, et al.
Publicado: (2003)

A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics
por: Bonello, Teresa T., et al.
Publicado: (2016)

Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells
por: Shen, D-W, et al.
Publicado: (2004)

Liver fatty acid binding protein expression in colorectal neoplasia
por: Lawrie, L C, et al.
Publicado: (2004)

The LIM-only protein, LMO4, and the LIM domain-binding protein, LDB1, expression in squamous cell carcinomas of the oral cavity
por: Mizunuma, H, et al.
Publicado: (2003)

Actin–tropomyosin distribution in non-muscle cells
por: Manstein, Dietmar J., et al.
Publicado: (2019)

Binding of TGF-β1 latency-associated peptide (LAP) to αvβ6 integrin modulates behaviour of squamous carcinoma cells
por: Thomas, G J, et al.
Publicado: (2002)

Induction of tetrasomy by human papillomavirus type 16 E7 protein is independent of pRb binding and disruption of differentiation
por: Southern, S A, et al.
Publicado: (2004)

Elevated expression and altered processing of fibulin-1 protein in human breast cancer
por: Greene, L M, et al.
Publicado: (2003)

Cytoskeletal tropomyosins: choreographers of actin filament functional diversity
por: Vindin, Howard, et al.
Publicado: (2013)

Tropomodulin: a cytoskeletal protein that binds to the end of erythrocyte tropomyosin and inhibits tropomyosin binding to actin
Publicado: (1990)

Expression of oestrogen receptor beta (ERβ1) protein in human breast cancer biopsies
por: Saunders, P T K, et al.
Publicado: (2002)

Characterisation of p53 status at the gene, chromosomal and protein levels in oesophageal adenocarcinoma
por: Doak, S H, et al.
Publicado: (2003)

E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia
por: Brooks, L A, et al.
Publicado: (2002)

Myosin and Tropomyosin Stabilize the Conformation of Formin-nucleated Actin Filaments
por: Ujfalusi, Zoltán, et al.
Publicado: (2012)

Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function
por: Bhat-Nakshatri, P, et al.
Publicado: (2004)

Aberrant expression of minichromosome maintenance protein-2 and Ki67 in laryngeal squamous epithelial lesions
por: Chatrath, P, et al.
Publicado: (2003)

Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer
por: Edwards, J, et al.
Publicado: (2003)

A novel diffuse large B-cell lymphoma-associated cancer testis antigen encoding a PAS domain protein
por: Liggins, A P, et al.
Publicado: (2004)

Diagnosis of oesophageal cancer by detection of minichromosome maintenance 5 protein in gastric aspirates
por: Williams, G H, et al.
Publicado: (2004)

Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients
por: van der Hage, J A, et al.
Publicado: (2004)

Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma
por: Sarela, A I, et al.
Publicado: (2002)

ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells
por: Mousli, M, et al.
Publicado: (2003)

The parathyroid hormone-related protein receptor is expressed in breast cancer bone metastases and promotes autocrine proliferation in breast carcinoma cells
por: Hoey, R P, et al.
Publicado: (2003)

Identification of heat shock protein 90 and other proteins as tumour antigens by serological screening of an ovarian carcinoma expression library
por: Luo, L-Y, et al.
Publicado: (2002)

Identification of an HLA-A(*)0201-restricted T-cell epitope derived from the prostate cancer-associated protein prostein
por: Kiessling, A, et al.
Publicado: (2004)

Immunofluorometric quantitation and histochemical localisation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarker
por: Hoffman, B R, et al.
Publicado: (2002)

Secretion of soluble complement inhibitors factor H and factor H-like protein (FHL-1) by ovarian tumour cells
por: Junnikkala, S, et al.
Publicado: (2002)

Expression of high-mobility-group-protein HMGI-C mRNA in the peripheral blood is an independent poor prognostic indicator for survival in metastatic breast cancer
por: Langelotz, C, et al.
Publicado: (2003)

Interaction between Ku80 protein and a widely used antibody to adenomatous polyposis coli
por: Roberts, G T, et al.
Publicado: (2003)

Tumour stage, node stage, p53 gene status, and bcl-2 protein expression as predictors of tumour response to platin-fluorouracil chemotherapy in patients with squamous-cell carcinoma of the head and neck
por: Fouret, P, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_kse15es9a0m7uco1nv3u01m0tb