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Individualised dosing strategy for high-dose carboplatin in patients with germ cell cancer
In contrast to conventional chemotherapy, carboplatin is still dosed per unit of body surface area (BSA) in high-dose chemotherapy protocols in clinical practice. To individualise dosing, a population pharmacokinetic model for poor-risk germ cell tumour patients receiving 1500 mg m(−2) carboplatin w...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394494/ https://www.ncbi.nlm.nih.gov/pubmed/12942106 http://dx.doi.org/10.1038/sj.bjc.6601215 |