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Individualised dosing strategy for high-dose carboplatin in patients with germ cell cancer

In contrast to conventional chemotherapy, carboplatin is still dosed per unit of body surface area (BSA) in high-dose chemotherapy protocols in clinical practice. To individualise dosing, a population pharmacokinetic model for poor-risk germ cell tumour patients receiving 1500 mg m(−2) carboplatin w...

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Detalles Bibliográficos
Autores principales: Kloft, C, Siegert, W, Jaehde, U
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394494/
https://www.ncbi.nlm.nih.gov/pubmed/12942106
http://dx.doi.org/10.1038/sj.bjc.6601215