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ERCC1 and BRCA1 mRNA expression levels in metastatic malignant effusions is associated with chemosensitivity to cisplatin and/or docetaxel

BACKGROUND: One of the major challenges in currently chemotherapeutic theme is lacking effective biomarkers for drug response and sensitivity. Our current study focus on two promising biomarkers, ERCC1 (excision repair cross-complementing group 1) and BRCA1 (breast cancer susceptibility gene 1). To...

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Detalles Bibliográficos
Autores principales: Wang, Lifeng, Wei, Jia, Qian, Xiaoping, Yin, Haitao, Zhao, Yang, Yu, Lixia, Wang, Tingting, Liu, Baorui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394535/
https://www.ncbi.nlm.nih.gov/pubmed/18402708
http://dx.doi.org/10.1186/1471-2407-8-97