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A Novel Role for PECAM-1 (CD31) in Regulating Haematopoietic Progenitor Cell Compartmentalization between the Peripheral Blood and Bone Marrow

Although the expression of PECAM-1 (CD31) on vascular and haematopoietic cells within the bone marrow microenvironment has been recognized for some time, its physiological role within this niche remains unexplored. In this study we show that PECAM-1 influences steady state hematopoietic stem cell (H...

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Detalles Bibliográficos
Autores principales: Ross, Ewan A., Freeman, Sylvie, Zhao, Yan, Dhanjal, Tarvinder S., Ross, Emma J., Lax, Sian, Ahmed, Zubair, Hou, Tie Zheng, Kalia, Neena, Egginton, Stuart, Nash, Gerard, Watson, Steve P., Frampton, Jon, Buckley, Christopher D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394654/
https://www.ncbi.nlm.nih.gov/pubmed/18523558
http://dx.doi.org/10.1371/journal.pone.0002338