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Adenosine Transporter ENT4 Is a Direct Target of EWS/WT1 Translocation Product and Is Highly Expressed in Desmoplastic Small Round Cell Tumor

BACKGROUND: Desmoplastic Small Round Cell Tumor (DSRCT) is a highly aggressive malignancy that affects mainly adolescents and young adults. A defining characteristic of DSRCT is a specific chromosomal translocation, t(11;22)(p13;q12), that fuses EWS with WT1, leading to a production of two isoforms...

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Detalles Bibliográficos
Autores principales: Li, Hongjie, Smolen, Gromoslaw A., Beers, Lisa F., Xia, Li, Gerald, William, Wang, Joanne, Haber, Daniel A., Lee, Sean Bong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394657/
https://www.ncbi.nlm.nih.gov/pubmed/18523561
http://dx.doi.org/10.1371/journal.pone.0002353