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Functional Diversification of Paralogous Transcription Factors via Divergence in DNA Binding Site Motif and in Expression

BACKGROUND: Gene duplication is a major driver of evolutionary innovation as it allows for an organism to elaborate its existing biological functions via specialization or diversification of initially redundant gene paralogs. Gene function can diversify in several ways. Transcription factor gene par...

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Detalles Bibliográficos
Autores principales: Singh, Larry N., Hannenhalli, Sridhar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394658/
https://www.ncbi.nlm.nih.gov/pubmed/18523562
http://dx.doi.org/10.1371/journal.pone.0002345