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NS1 Specific CD8(+) T-Cells with Effector Function and TRBV11 Dominance in a Patient with Parvovirus B19 Associated Inflammatory Cardiomyopathy

BACKGROUND: Parvovirus B19 (B19V) is the most commonly detected virus in endomyocardial biopsies (EMBs) from patients with inflammatory cardiomyopathy (DCMi). Despite the importance of T-cells in antiviral defense, little is known about the role of B19V specific T-cells in this entity. METHODOLOGY A...

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Detalles Bibliográficos
Autores principales: Streitz, Mathias, Noutsias, Michel, Volkmer, Rudolf, Rohde, Maria, Brestrich, Gordon, Block, Andrea, Klippert, Katrin, Kotsch, Katja, Ay, Bernhard, Hummel, Michael, Kühl, Uwe, Lassner, Dirk, Schultheiss, Heinz-Peter, Volk, Hans-Dieter, Kern, Florian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394660/
https://www.ncbi.nlm.nih.gov/pubmed/18523634
http://dx.doi.org/10.1371/journal.pone.0002361