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Bimodal and Hysteretic Expression in Mammalian Cells from a Synthetic Gene Circuit

In order to establish cells and organisms with predictable properties, synthetic biology makes use of controllable, synthetic genetic devices. These devices are used to replace or to interfere with natural pathways. Alternatively, they may be interlinked with endogenous pathways to create artificial...

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Detalles Bibliográficos
Autores principales: May, Tobias, Eccleston, Lee, Herrmann, Sabrina, Hauser, Hansjörg, Goncalves, Jorge, Wirth, Dagmar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394661/
https://www.ncbi.nlm.nih.gov/pubmed/18523635
http://dx.doi.org/10.1371/journal.pone.0002372