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Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains

BACKGROUND: Francisella tularensis subspecies tularensis and holarctica are pathogenic to humans, whereas the two other subspecies, novicida and mediasiatica, rarely cause disease. To uncover the factors that allow subspecies tularensis and holarctica to be pathogenic to humans, we compared their ge...

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Detalles Bibliográficos
Autores principales: Rohmer, Laurence, Fong, Christine, Abmayr, Simone, Wasnick, Michael, Larson Freeman, Theodore J, Radey, Matthew, Guina, Tina, Svensson, Kerstin, Hayden, Hillary S, Jacobs, Michael, Gallagher, Larry A, Manoil, Colin, Ernst, Robert K, Drees, Becky, Buckley, Danielle, Haugen, Eric, Bovee, Donald, Zhou, Yang, Chang, Jean, Levy, Ruth, Lim, Regina, Gillett, Will, Guenthener, Don, Kang, Allison, Shaffer, Scott A, Taylor, Greg, Chen, Jinzhi, Gallis, Byron, D'Argenio, David A, Forsman, Mats, Olson, Maynard V, Goodlett, David R, Kaul, Rajinder, Miller, Samuel I, Brittnacher, Mitchell J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394750/
https://www.ncbi.nlm.nih.gov/pubmed/17550600
http://dx.doi.org/10.1186/gb-2007-8-6-r102