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Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains

BACKGROUND: The distributed genome hypothesis (DGH) posits that chronic bacterial pathogens utilize polyclonal infection and reassortment of genic characters to ensure persistence in the face of adaptive host defenses. Studies based on random sequencing of multiple strain libraries suggested that fr...

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Detalles Bibliográficos
Autores principales: Hogg, Justin S, Hu, Fen Z, Janto, Benjamin, Boissy, Robert, Hayes, Jay, Keefe, Randy, Post, J Christopher, Ehrlich, Garth D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394751/
https://www.ncbi.nlm.nih.gov/pubmed/17550610
http://dx.doi.org/10.1186/gb-2007-8-6-r103