Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes

BACKGROUND: Chromosome 15 contains many segmental duplications, including some at 15q11-q13 that appear to be responsible for the deletions that cause Prader-Willi and Angelman syndromes and for other genomic disorders. The current version of the human genome sequence is incomplete, with seven gaps...

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Detalles Bibliográficos
Autores principales: Makoff, Andrew J, Flomen, Rachel H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394762/
https://www.ncbi.nlm.nih.gov/pubmed/17573966
http://dx.doi.org/10.1186/gb-2007-8-6-r114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394762/
https://www.ncbi.nlm.nih.gov/pubmed/17573966
http://dx.doi.org/10.1186/gb-2007-8-6-r114

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