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Dealing with structural variability in molecular replacement and crystallographic refinement through normal-mode analysis
Normal-mode analysis (NMA) can be used to generate multiple structural variants of a given template model, thereby increasing the chance of finding the molecular-replacement solution. Here, it is shown that it is also possible to directly refine the amplitudes of the normal modes against experimenta...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394787/ https://www.ncbi.nlm.nih.gov/pubmed/18094466 http://dx.doi.org/10.1107/S0907444907053516 |