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The JCSG MR pipeline: optimized alignments, multiple models and parallel searches
The success rate of molecular replacement (MR) falls considerably when search models share less than 35% sequence identity with their templates, but can be improved significantly by using fold-recognition methods combined with exhaustive MR searches. Models based on alignments calculated with fold-r...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394805/ https://www.ncbi.nlm.nih.gov/pubmed/18094477 http://dx.doi.org/10.1107/S0907444907050111 |