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The JCSG MR pipeline: optimized alignments, multiple models and parallel searches

The success rate of molecular replacement (MR) falls considerably when search models share less than 35% sequence identity with their templates, but can be improved significantly by using fold-recognition methods combined with exhaustive MR searches. Models based on alignments calculated with fold-r...

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Detalles Bibliográficos
Autores principales: Schwarzenbacher, Robert, Godzik, Adam, Jaroszewski, Lukasz
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394805/
https://www.ncbi.nlm.nih.gov/pubmed/18094477
http://dx.doi.org/10.1107/S0907444907050111