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Protein interactions in human genetic diseases
We present a novel method that combines protein structure information with protein interaction data to identify residues that form part of an interaction interface. Our prediction method can retrieve interaction hotspots with an accuracy of 60% (at a 20% false positive rate). The method was applied...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395246/ https://www.ncbi.nlm.nih.gov/pubmed/18199329 http://dx.doi.org/10.1186/gb-2008-9-1-r9 |