An improved method for detecting and delineating genomic regions with altered gene expression in cancer

Genomic regions with altered gene expression are a characteristic feature of cancer cells. We present a novel method for identifying such regions in gene expression maps. This method is based on total variation minimization, a classical signal restoration technique. In systematic evaluations, we sho...

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Detalles Bibliográficos
Autores principales: Nilsson, Björn, Johansson, Mikael, Heyden, Anders, Nelander, Sven, Fioretos, Thoas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395254/
https://www.ncbi.nlm.nih.gov/pubmed/18208590
http://dx.doi.org/10.1186/gb-2008-9-1-r13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395254/
https://www.ncbi.nlm.nih.gov/pubmed/18208590
http://dx.doi.org/10.1186/gb-2008-9-1-r13

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