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An improved method for detecting and delineating genomic regions with altered gene expression in cancer
Genomic regions with altered gene expression are a characteristic feature of cancer cells. We present a novel method for identifying such regions in gene expression maps. This method is based on total variation minimization, a classical signal restoration technique. In systematic evaluations, we sho...
Autores principales: | Nilsson, Björn, Johansson, Mikael, Heyden, Anders, Nelander, Sven, Fioretos, Thoas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395254/ https://www.ncbi.nlm.nih.gov/pubmed/18208590 http://dx.doi.org/10.1186/gb-2008-9-1-r13 |
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