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C-erbB-2 or mutant Ha-ras induced malignant transformation of immortalized human ovarian surface epithelial cells in vitro

Ovarian cancer is believed to develop from the ovarian surface epithelium through the accumulation of aberrations of oncogenes and/or tumor suppressor genes. However, it is unclear how the gene abnormalities are involved in ovarian carcinogenesis. To elucidate the process, we transfected genes repor...

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Detalles Bibliográficos
Autores principales: Kusakari, T, Kariya, M, Mandai, M, Tsuruta, Y, Hamid, A A, Fukuhara, K, Nanbu, K, Takakura, K, Fujii, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395276/
https://www.ncbi.nlm.nih.gov/pubmed/14676809
http://dx.doi.org/10.1038/sj.bjc.6601423