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Autocrine Transforming Growth Factor-β Growth Pathway in Murine Osteosarcoma Cell Lines Associated with Inability to Affect Phosphorylation of Retinoblastoma Protein

Purpose. Production of active transforming growth factor-β (TGF-β ) by human osteosarcoma may contribute to malignant progression through mechanisms that include induction of angiogenesis, immune suppression and autocrine growth stimulation of tumor cell growth.To study events associated with induct...

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Detalles Bibliográficos
Autores principales: Navid, Fariba, Letterio, John J., Yeung, Choh L., Pegtel, Michiel, Helman, Lee J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395437/
https://www.ncbi.nlm.nih.gov/pubmed/18521287
http://dx.doi.org/10.1080/13577140020008057