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TNP-470 Suppresses the Tumorigenicity of HT1080 Fibrosarcoma Tumor Through the Inhibition of VEGF Secretion From the Tumor Cells

Angiogenesis inhibitors are a novel class of promising therapeutic agents for treating cancer. TNP-470, a systemic analogue of fumagillin, is an angiogenesis inhibitor capable of suppressing the tumorigenicity in several animal models even though the mechanisms of action have not been completely cla...

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Detalles Bibliográficos
Autores principales: Kaya, Mitsunori, Wada, Takuro, Nagoya, Satoshi, Kawaguchi, Satoshi, Yamashita, Toshihiko, Yamamoto, Nobuyuki, Yoshimoto, Mitsunori, Okada, Futoshi, Ishii, Seiichi
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395463/
https://www.ncbi.nlm.nih.gov/pubmed/18521314
http://dx.doi.org/10.1080/13577140120099182