COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro

BACKGROUND: An increasing number of reports is challenging the notion that the antitumor potential of the selective COX-2 inhibitor celecoxib (Celebrex(®)) is mediated primarily via the inhibition of COX-2. We have investigated this issue by applying two different analogs of celecoxib that different...

Descripción completa

Detalles Bibliográficos
Autores principales: Chuang, Huan-Ching, Kardosh, Adel, Gaffney, Kevin J, Petasis, Nicos A, Schönthal, Axel H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396175/
https://www.ncbi.nlm.nih.gov/pubmed/18485224
http://dx.doi.org/10.1186/1476-4598-7-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396175/
https://www.ncbi.nlm.nih.gov/pubmed/18485224
http://dx.doi.org/10.1186/1476-4598-7-38

Ejemplares similares