Inhibition of p38 MAPK Suppresses Inflammatory Cytokine Induction by Etoposide, 5-Fluorouracil, and Doxorubicin without Affecting Tumoricidal Activity

Cancer patients undergoing treatment with systemic cancer chemotherapy drugs often experience debilitating fatigue similar to sickness behavior, a normal response to infection or tissue damage caused by the production of the inflammatory cytokines IL-1β, TNF-α, and IL-6. The p38 mitogen activated pr...

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Detalles Bibliográficos
Autores principales: Elsea, Collin R., Roberts, Daniel A., Druker, Brian J., Wood, Lisa J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396285/
https://www.ncbi.nlm.nih.gov/pubmed/18523641
http://dx.doi.org/10.1371/journal.pone.0002355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396285/
https://www.ncbi.nlm.nih.gov/pubmed/18523641
http://dx.doi.org/10.1371/journal.pone.0002355

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