Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron

RNA interference (RNAi) is a powerful approach to inhibit human immunodeficiency virus type 1 (HIV-1) replication. However, HIV-1 can escape from RNAi-mediated antiviral therapy by selection of mutations in the targeted sequence. To prevent viral escape, multiple small interfering RNAs (siRNAs) agai...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ying Poi, Haasnoot, Joost, ter Brake, Olivier, Berkhout, Ben, Konstantinova, Pavlina
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396423/
https://www.ncbi.nlm.nih.gov/pubmed/18346971
http://dx.doi.org/10.1093/nar/gkn109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396423/
https://www.ncbi.nlm.nih.gov/pubmed/18346971
http://dx.doi.org/10.1093/nar/gkn109

Ejemplares similares