Cargando…

Uteroplacental insufficiency down regulates insulin receptor and affects expression of key enzymes of long-chain fatty acid (LCFA) metabolism in skeletal muscle at birth

BACKGROUND: Epidemiological studies have revealed a relationship between early growth restriction and the subsequent development of insulin resistance and type 2 diabetes. Ligation of the uterine arteries in rats mimics uteroplacental insufficiency and serves as a model of intrauterine growth restri...

Descripción completa

Detalles Bibliográficos
Autores principales: Germani, Daniela, Puglianiello, Antonella, Cianfarani, Stefano
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396605/
https://www.ncbi.nlm.nih.gov/pubmed/18485240
http://dx.doi.org/10.1186/1475-2840-7-14